25: Jeremy the director smashes M&Ms during a studio meeting after the studio head informs him he'll have to cut the part about killing the dog. The birth of something new.
45: DeNiro dines with investors and gets a call from his ex-wife. He wants to know if she's sleeping with someone else. She refuses to tell him or see him. He's distracted seeing an agent who needs to tell Bruce Willis to lose the beard. Now that I'm aware.
60: DeNiro celebrates with Jeremy after he cut a new, happier ending for the dog movie. DeNiro urges Bruce Willis' agent to tell him to cut the beard. With his ex-wife and therapist he attempts to reveal things and hear things that will hopefully result in an amicable separation. He wants to hear her talk about the new guy in her life but there isn't time. There's no going back now.
-45: DeNiro wakes up, does yoga, and the woman he slept with the night before enters and reminds him he slept with her and offered her a movie deal. Discovery.
-25: At a funeral DeNiro learns his daughter slept with the deceased. Later DeNiro argues with the married man sleeping with his wife and later argues with Willis. Eventually Willis shaves, an indication the movie will do well. The final turning point.